Cognition, Behavior, and Memory
Author: Lucia Alba-Ferrara | email: lucia.alba@fultra.org
Bautista Elizalde ACEVEDO 2°, Valentina Aguero Vera 2°, Silvia Kochen 1°, Lucia Alba-Ferrara 1°, 1°, 1°, 1°, 1°, 1°, 1°
1° ENyS CONICET
2° IIMT Universidad Austral
3°
4°
Temporal lobe epilepsy (TLE) could affect eloquent areas, such as those underlying language processing, when the epileptogenic zone overlaps linguistic nodes. We applied a non-invasive task called International Lexical Decision Task (ILDT), and it uses dichotic listening, overcoming the tongue spoken by the participant [1], to assess the lateralization of lexical processing in refractory TLE. Method: Patients with left TLE (LTLE) (N=12), right TLE (RTLE) (N=15) and controls (N=16) were evaluated using ILDT. An ANCOVA analysis was performed, with the stimulus presented to the left visual field, to the right, or a baseline condition as an intrasubject factor and group as a between subject factor. Result: A main effect of stimuli was found (F1.35)=21,P<0.05), by which all type of stimuli differed from each other. The baseline improved performance (M=54.78,SD=3.41), stimuli presented to the right obtained an intermediate performance (M=36.07,SD=1.32) and to the left resulted in lower performance (M=29.30,SD=1.46). A main effect of group was found (F(2.71)=10,P<0.05). Pairwise comparisons showed that the controls (M=52.07,SD=2.67) outperformed both patient groups. The groups of LTLE (M=31.74,SD=3.96) and RTLE (M=36.35,SD=2.71), did not differ from each other. A trend of interaction between group and stimulus was found by which LTLE patients found particularly difficult to identify stimuli presented to the right visual field, although such trend did not reach significance.