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238 | Using dynamical metrics hypergraphs to study epilepsy dynamics.

Theoretical and Computational Neuroscience

Author: Dalma Anahi bilbao | email: bilbaodalmaanahi@gmail.com


Dalma Anahi Bilbao , Hugo Aimar , Diego Martin Mateos

1° IMAl conicet Santa Fe

The analysis of connectivity networks is one of the fundamental tools in the study of neuroscience. Generally, this analysis is carried out using graph theory, which describes the pairwise relationship between the components of a network. However, in the brain, the relationship between its components (neurons, brain areas, etc.) has more complex relationships. To address this problem, hypergraph theory can represent the multiple relationships between its components. In this work, we use the metric hypergraph method to study brain dynamics during an epileptic seizure. Initially, we applied the basic Kuramoto model, which simulates a hypersynchronisation of the system (seizure). Subsequently, magnetoencephalography signals from two particular cases of generalized epilepsy were analyzed. Through this analysis, we can study the dynamics of the synchronization phenomenon in an epileptic seizure.

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